Web图:Nature Reviews Rheumatology对该文研究亮点配图 迄今为止,已有240余个单核苷酸多态性(SNP)被发现与炎症性肠病(IBD)发病风险相关,而许多疾病风险相关SNP位于非编码区域,确定这些非编码区SNP相关的致病机制是疾病研究的重要挑战。 rs4728142此前已报道和IBD的一种亚型溃疡性结肠炎(UC)相关,它可能在体外影响转录因子结合DNA … Web1 de dic. de 2024 · In this review, we have systemically reviewed the pathogenesis of IBD and highlighted recent advances in host genetic factors, gut microbiota, and environmental factors and, especially, in abnormal innate and adaptive immune responses and their interactions, which may hold the keys to identify novel predictive or prognostic …
Improving IBD outcomes in the era of many treatment options
WebBiological sciences articles within Nature Reviews Gastroenterology ... An improved understanding of thiopurine metabolism has enabled individualized dosing of these agents in patients with IBD. Web12 de ene. de 2024 · 【主编推荐语】Nature Reviews Gastroenterology and Hepatology上发表的年度回顾,介绍了2024年的IBD治疗药物的重要临床试验结果,包括IL-23p19抗体、JAK抑制剂、口服整合素α4抑制剂等。 (@aluba) Improving IBD outcomes in the era of many treatment options 2024-01-12, doi:10.1038/s41575-022-00738-z IBD治疗 综述 … c and a cabinets
A Comprehensive Review and Update on the Pathogenesis of …
Web9 de mar. de 2024 · This review will discuss the pathogenesis of IBD, with emphasis on mucosal immunity, along with mechanisms of current and emerging biological therapies. Data from animal and experimental studies will be referred to when necessary as supportive evidence. Role of innate immunity in IBD pathogenesis Web14 de ene. de 2024 · Environmental and genetic factors have been demonstrated to contribute to the development of inflammatory bowel disease (IBD). Recent studies suggested that the food additive; titanium dioxide (TiO2) might play a causative role in the disease. Therefore, in the present study we aimed to explore the interaction between the … WebNature Reviews Materials is a monthly peer-reviewed scientific journal published by Nature Portfolio. It was established in 2016. [1] The journal covers all topics within materials … fish native to united states