WebApr 14, 2024 · Abstract. Mdm2 and its homologue MdmX form an E3-ligase complex that is best understood as the major regulator of p53. Yet Mdm2 and MdmX have functions in cells that are independent of their ability to degrade p53. Amongst the functions regulated by Mdm2 is cell migration, although the molecular mechanism(s) involved have not been … WebGoogle Scholar provides a simple way to broadly search for scholarly literature. From one place, you can search across many disciplines and sources: articles, theses, books, abstracts and court ...
Abstract CT101: Phase I study of the T-cell receptor-like antibody ...
WebApr 14, 2024 · Abstract. Purpose: It has become increasingly clear that the activation of both the innate and adaptive immune systems is vital to provide the best outcomes with immunotherapies. As part of the adaptive immune response, checkpoint inhibitors (CIs) have shown promise in the clinic, but seem to only work in a small subset of cancers with … WebApr 14, 2024 · Abstract. Background: Glucocorticoid-Induced Tumor Necrosis Factor Receptor-related protein (GITR) is a co-stimulatory pathway that when triggered has … the hunger games actress familiarly crossword
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