Cisplatin a549 xenograft
WebMay 28, 2024 · In xenograft models, osimertinib significantly inhibited tumor growth, however, as expected, in 50% of mice drug-resistance developed. A combination of osimertinib with pemetrexed or cisplatin prevented or at … WebSep 14, 2024 · A549 cells were seeded in 96-well plates and cultured for 24 hours, then treated with varying concentrations of rhMG53 (0.05-100 μg/ml) or rhMG53 plus cisplatin (5 μM) for either 48 hours or 72 hours. Cells were detached by 0.25% Trypsin-EDTA solution, and their viability were quantified by flow cytometry (CytoFLEX S system, Beckman …
Cisplatin a549 xenograft
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WebJul 15, 2024 · A549/DDP cells with TIMR59 knockdown was more sensitive to cisplatin treatment in a xenograft model. Moreover, A549/DDP cells exhibited increased glucose … WebApr 8, 2014 · The MTT assay demonstrated that cisplatin exhibits a dose‑dependent cytotoxicity in A549 cells and synergizes with radiation to promote the cell‑killing effect of radiation. In the xenograft mouse model of Lewis cells, cisplatin plus ionizing radiation (IR) (five doses of 2 Gy) yielded the most significant tumor suppression.
WebNov 29, 2024 · This study revealed that cisplatin resistant A549 lung cancer cells can be identified by their increased levels of mitochondrial mass. However, Mito-High cells … WebOct 1, 2024 · A549 human lung carcinoma cells were obtained from the Korean Cell Line Bank (Seoul, Republic of Korea) and cultured in RPMI 1640 medium with 10% …
Weboma A549 cells and cisplatin (DDP) resistant A549 cells (A549DDP) were obtained from the American Type Culture ... xenograft tumor was visualized with the indicated antibodies. Ma et al. World Journal of Surgical Oncology (2015) 13:80 Page 4 of 6. A549/sCLU solid tumors (Figure 4). These findings sug- WebTargeting of the nano‐zinc carrier to A549/DDP or A549 cells in vivo was detected after subcutaneous injection in a mouse xenograft tumor model. A549/DDP or A549 cells (1 × 10 6 cells) in 50 μL of PBS were injected into the armpits of 4‐week‐old nude mice (BALB/c, nu/nu; SIPPR‐BK Laboratory Animal Co. Ltd, Shanghai, China) using a 25 ...
WebJul 3, 2024 · (B) A549 xenograft tumors were treated with citrate (twice daily from day 14 to 40), cisplatin or citrate/cisplatin combination (3 doses of cisplatin at 4 mg/kg on days 14, 17 and 20 were given by ...
WebSep 2, 2024 · In the beginning, under both in vitro and in vivo conditions (A549 and H460 cells as well as A549 xenograft model) treated with external heat before and after intravascular administration of heat-activated thermosensitive liposome containing cisplatin (HTLC), exhibited rapid accumulation of drug in the tumor as well as a subsequent … images to make you feel cozyWebIn the present study, the sequence‑dependent effects of GEM and CDDP were investigated in the NSCLC cell line, A549. Significantly increased rates of inhibition and cell cycle … images tombolaWebThe A549 cell line was derived from a human lung adenocarcinoma and has been used in numerous studies to investigate various aspects of lung cancer biology, including cell … images tomates vertesWebJan 12, 2024 · Here, we show that this combination enhances the anti-cancer effect of cisplatin in both in vitro cell lines and in vivo xenograft mouse models of cisplatin-sensitive and -resistant lung, ovarian ... list of countries in se asiaWebFurthermore, combined treatment with intravenous injections of Lps-pVAX-LKB1 and intraperitoneal injection of low-dose cisplatin into mice bearing experimental A549 lung metastasis demonstrated significant (P<0.01) decrease in … images tomballWebOct 7, 2013 · A Balb/c nude mouse xenograft model using A549 cells was previously established. The mice were randomly divided into normal, mock, Ke, cisplatin (DDP), and co-formulated (Ke + DDP) groups. After 15 days of drug administration, the animals were sacrificed, body weight and tumor volume were recorded, and the tumor-inhibiting rate … images tom brady and familyWeb2 days ago · Complex 11 showed a significant in vivo anticancer effect, revealed by its inhibiting effects on tumor growth in T24 xenograft mice without any renal pathological changes or influence on renal function. ... Complexes 36–40 were tested against lung carcinomas A549 and A549/DDP, cisplatin-insensitive cells, and normal healthy (HL … images tom brady